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CAR-T cells engineered to attack two leukemia proteins show promise in preclinical tests

T-cell acute lymphoblastic leukemia (T-ALL) is a highly aggressive form of blood cancer that can occur in both children and adults. It is characterized by failures in the maturation of T-lymphocytes, key immune cells involved in the defense against infections and cancer, which, instead of performing their function, proliferate uncontrollably in the bone marrow. While the cure rate in children exceeds 80%, in adults it remains at around 40% and is associated with a high probability of relapse following chemotherapy.

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3 hours ago
By Halo

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